P-143: Histomorphometric Evaluation ofSmall Intestine during Pregnancy in Rat
نویسندگان
چکیده مقاله:
Background: Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Materials and Methods: Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 pregnancy) were collected. Villous height and width and thickness of tunica submucosa, tunica muscularis entirely and separately (circular and longitudinal layers) were measured on transverse sections. The data were analyzed by one-way ANOVA and Tukey post-hoc test (SPSS 11.5). P<0.05 was considered significant. Results: Villi length in duodenum decreased until day 14 of pregnancy and then increased near parturition (p<0.05). In the jejunum this item increased during growth of fetuses (p<0.001). In the ileum, the length of villi decreased with age until day 14 of pregnancy and did not increase until parturition (p<0.05). Villi width in duodenum and jejunum increased during pregnancy, but in ileum decreased until day 14 and then increased in day 21 (p<0.05). Lamina properia and tunica muscularis diameters in duodenum did not have any remarkable changes during pregnancy (p<0.05). However, in jejunum, they were increased until day 14 pregnancy (p<0.05) and remained unchanged until the end of pregnancy. Most diameters of them were in day 14 of pregnancy in ileum and then decreased until day 21 of pregnancy (p<0.05). Conclusion: More capacity of duodenum to digest food intake during pregnancy was observed by increasing villi length and muscular layer thickness. Furthermore, along with the progress of gestation greatest histomorphologic change in small intestine was observed in the jejunum to increase absorption of nutritional needs during pregnancy. While, the reduction in the ileum histomorphologic indices during pregnancy, control the absorption of excess produced amino acids and glucose by hyperphagia.
منابع مشابه
Histomorphometric changes of small intestine in pregnant rat
Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 of pregnancy) were collected. Villous height a...
متن کاملHistomorphometric changes of small intestine in pregnant rat
Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 of pregnancy) were collected. Villous height a...
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food intake of rats increases during pregnancy. this requires changes in the structure of the small intestine to absorb additional food. the aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. duodenum, jejunum and ileum of 18 pregnant sprague-dawley rats (day 7, 14 and 21 of pregnancy) were collected. villous height a...
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عنوان ژورنال
دوره 8 شماره 2.5
صفحات 154- 154
تاریخ انتشار 2014-07-01
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